The cells were then treated with either Tamoxifen (Sigma-Aldrich, St. expression of the genes. Results DCM-DS was cytotoxic to the MCF-7 cells in a time-and dose-dependent manner. The IC50 values of DCM-DS at 24, 48 and 72?hours were 20.3??2.8, 17.8??1.5 and 15.5??0.5?g/mL, respectively. Cell cycle analysis revealed that DCM-DS induced G0/G1 and G2/M phase cell … Continue reading The cells were then treated with either Tamoxifen (Sigma-Aldrich, St